A crash closed Interstate 85 South near Exit 170 (U.S. Route 70) in Orange County Wednesday morning.
Around 1:40 a.m., a tractor-trailer and a car were involved in a crash near Hillsborough. The State Highway Patrol (SHP) said both drivers were extricated and taken to the hospital with serious injuries.
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The road has reopened. It's unclear if charges will be filed, according to the SHP.
WRAL News is working to learn what caused the crash.